Los Mochis (Spanish pronunciation: [loz ˈmotʃis]) is a coastal city in northern Sinaloa, Mexico. It serves as the municipal seat of the municipality of Ahome. As of the 2010 census, the population was 256,613, which was 61 percent of the municipality's population.
Los Mochis is the western terminus of the Chihuahua-Pacific Railroad, or ChePe, which passes through the scenic Copper Canyon. This railway was originally conceived by Albert K. Owen and approved by President Porfirio Díaz as a trade route linking the cattle markets in Kansas City with the nearest port on the Pacific Ocean, Topolobampo.
Today the North Pacific irrigation region (Sinaloa-Sonora) in which the Fort Valley is the largest district and is the principal agricultural area of Sinaloa, containing over 70% of all irrigated land and producing sugar cane, cotton, rice, flowers, and many types of vegetables. The valley is one of the largest producers of mangoes in Mexico. Air transportation is provided by Los Mochis International Airport. Nearby Topolobampo is the second largest natural deepwater port in the world, and is known for its commercial fishing and increasingly important role in shipping.