Minneapolis (/ˌmɪniˈæpəlɪs/) is the county seat of Hennepin County, and larger of the Twin Cities, the 16th-largest metropolitan area in the United States, containing about 3.5 million residents. As of 2015, Minneapolis is the largest city in the state of Minnesota and 46th-largest in the United States with a population of 410,939. Minneapolis and Saint Paul anchor the second-largest economic center in the Midwest, after Chicago.
Minneapolis lies on both banks of the Mississippi River, just north of the river's confluence with the Minnesota River, and adjoins Saint Paul, the state's capital. The city is abundantly rich in water, with twenty lakes and wetlands, the Mississippi River, creeks and waterfalls, many connected by parkways in the Chain of Lakes and the Grand Rounds National Scenic Byway. It was once the world's flour milling capital and a hub for timber. In the 21st century, it is the primary business center between Chicago and Seattle, with Minneapolis proper containing America's fifth-highest concentration of Fortune 500 companies. As an integral link to the global economy, Minneapolis is categorized as a global city. Noted for its strong music and performing arts scenes, Minneapolis is home to both the award-winning Guthrie Theater and the historic First Avenue nightclub, the latter of which helped launch the career of musical icon Prince.
Minneapolis' name is attributed to Charles Hoag, the city's first schoolteacher, who combined mni, a Dakota Sioux word for water, and polis, the Greek word for city.