Pulaski County is a county located in South Central Missouri. As of the 2010 census, the population was 52,274. Its county seat is Waynesville. The county was organized in 1833 and named for Kazimierz Pułaski, a Polish patriot who died fighting in the American Revolution.
Pulaski County is the site of Fort Leonard Wood, a U.S. Army installation base. It comprises the Fort Leonard Wood, MO Micropolitan Statistical Area.