Spartanburg is the largest city in and the county seat of Spartanburg County, South Carolina, United States, and the twelfth largest city by population in the state. Spartanburg has a municipal population of 37,013 and an urban population of 180,786 at the 2010 census. The Spartanburg Metropolitan Statistical Area, corresponding to Spartanburg County and Union County had a population of 316,997 as of the 2012 census estimate and Revised Delineations of Metropolitan Statistical Areas.
Spartanburg is the second-largest city in the greater Greenville-Spartanburg-Anderson Combined Statistical Area which had a population of 1,266,995 at the 2010 census. It is part of a 10-county region of northwestern South Carolina known as "The Upstate," and is located 98 miles (158 km) northwest of Columbia, 80 miles (130 km) west of Charlotte, North Carolina, and about 190 miles (310 km) northeast of Atlanta, Georgia.