Springfield is the third largest city in the state of Missouri and the county seat of Greene County. According to the 2010 census data, the population was 159,498, an increase of 5.2% since the 2000 census. It is one of the two principal cities of the Springfield-Branson Metropolitan Area, which has a population of 537,631 and includes the counties of Christian, Dallas, Greene, Polk, Webster, Stone and Taney. Springfield's nickname is the "Queen City of the Ozarks" and is known as the "Birthplace of Route 66". It is also home of several universities including Missouri State University, Drury University, and Evangel University.